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TAK-448 acetate

CAS No. 1470374-22-1

TAK-448 acetate ( MVT-602 acetate )

产品货号. M29792 CAS No. 1470374-22-1

TAK-448 is a KISS1R protein agonist as a oligopeptide analog of kisspeptin,TAK-448 acetate (MVT-602 acetate) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥2657 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
5MG ¥2657 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货

生物学信息

  • 产品名称
    TAK-448 acetate
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    TAK-448 is a KISS1R protein agonist as a oligopeptide analog of kisspeptin,TAK-448 acetate (MVT-602 acetate) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM.
  • 产品描述
    TAK-448 is a KISS1R protein agonist as a oligopeptide analog of kisspeptin,TAK-448 acetate (MVT-602 acetate) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM.(In Vivo):TAK-448 acetate (0.01-3 mg/kg; given i.h.; dosings on day 0 and 28) has greater anti-tumor effects in VCaP xenograft model.
  • 同义词
    MVT-602 acetate
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    IC50: 460 pM (KISS1R)
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1470374-22-1
  • 分子量
    1285.4
  • 分子式
    C60H84N16O16
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    ——
  • 化学全称
    Sequence:Ac-D-Tyr-D-Trp-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

Nishizawa N, et al. Design and Synthesis of an Investigational Nonapeptide KISS1 Receptor (KISS1R) Agonist, Ac-d-Tyr-Hydroxyproline (Hyp)-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2 (TAK-448), with Highly PotentTestosterone-Suppressive Activity and Excellent Water Solubility. J Med Chem. 2016 Oct 13;59(19):8804-8811.
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